What's inside the SMA Treatment Guide?
Currently, there are three treatment options available in Canada for people with SMA:
PRSPINRAZATM (nusinersen injection),
PrZOLGENSMA® (onasemnogene abeparvovec)
and PrEVRYSDI® (risdiplam).
How do you know which one is best for you, or your child?
The SMA Treatment Guide provides you with the most important information on each of the treatment options available for SMA, including 9 topics:
Understanding
SMA

Approved therapies
in Canada

How do the
treatments work?

How are the
treatments given?

Patient
Experience

Treatment
Sequencing

Accessing
Therapy

Possible
Side Effects

Warnings and
Precautions

Topic 1
Understanding
SMA
Topic 2
Approved therapies
in Canada
Topic 3
How do the
treatments work?
Topic 4
How are the
treatments given?
Topic 5
Patient
Experience
Topic 6
Treatment
Sequencing
Topic 7
Accessing
Therapy
Topic 8
Possible
Side Effects
Topic 9
Warnings and
Precautions
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Understanding
SMA

Approved therapies
in Canada

How do the
treatments work?

How are the
treatments given?

Patient
Experience

Treatment
Sequencing

Accessing
Therapy

Possible
Side Effects

Warnings and
Precautions

The earlier treatment can begin, and the longer you can stay on therapy, the better the outcome will be.1
Download the full SMA Treatment Guide, to gain a better understanding of your treatment options so that you can have an informed discussion with your healthcare professional.
Read all about each treatment below:
PRSPINRAZATM
(nusinersen injection) PrZOLGENSMA®
(onasemnogene abeparvovec) PrEVRYSDI®
(risdiplam)
REFERENCE
1. Prior TW, Leach ME, Finanger E. Spinal Muscular Atrophy. 2000 Feb 24 [Updated 2019 Nov 14]. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1352/